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psychopharmacologyinstitute.com
Buprenorphine for Opioid Use Disorder: Mechanism of Action
. Let me start with the buprenorphine mechanism of action and rationale for therapeutic use. In the brain, naturally produced opioids called endorphins are released in the synapse and activate the opioid receptors producing a classic mu-opioid response. The effects include: analgesia, euphoria, constipation and respiratory depression ...
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