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  1. Could 'The Last of Us' really happen? USF mycology expert breaks …

    May 1, 2025 · "The Last of Us" is loosely based on a genus of real fungi called Ophiocordyceps, which infects a few animal species, including ants and spiders, and hijacks their behavior.

  2. Cordyceps brain infection | The Last of Us Wiki | Fandom

    The Cordyceps brain infection (abbreviated as CBI) is a parasitic fungal infection that has devastated mankind in The Last of Us series. In The Last of Us, a mutated strain of the …

  3. The Last of Us cordyceps myths debunked by real fungus expert!

    Jan 2, 2026 · In HBOs The Last of Us, the mutated strain of the Cordyceps fungus infects humanity. How plausible is this science fiction scenario?

  4. Cordyceps fungus: ‘The Last of Us’ co-star thriving outside the ...

    Apr 11, 2025 · In the new season, five years have passed since Joel and Ellie’s treacherous journey across America to the fortified mountain community of Jackson, Wyoming. Here, they …

  5. Zombie Fungus in The Last of Us: Could It Infect Humans?

    May 15, 2025 · The zombie fungus in The Last of Us is based on a real-life Cordyceps species. It can’t infect humans — our body heat, biology, and immune systems are way too complex.

  6. "The Last of Us": Could Fungi Spell Doom?

    “The Last of Us” tells the story of a fungal infection zombie apocalypse. Is this scenario realistic? Sharjeel Ahmad, MD, an infectious disease specialist with OSF HealthCare, dives into that …

  7. The Last Of Us: The science behind the real 'zombie' fungus - Sky News

    Apr 20, 2025 · The second season of HBO's The Last Of Us is under way, bringing viewers back into a world where humanity has been pushed to the brink of extinction by a fungus that infects …

  8. Can climate change really create zombie fungi, like in "The Last of Us ...

    Apr 12, 2025 · Can cordyceps infect humans? In "The Last of Us," cordyceps — a real fungus that infects insects — evolves into a harmful pathogen for humans due to a warming climate.

  9. The Last of Us” Apocalypse Is Not Realistic, But Rising Threat of ...

    Feb 5, 2023 · Although “The Last of Us” may be more fiction than fact, Roberts says there’s a sentiment of gratitude among infectious disease specialists for the rise in awareness of fungal …

  10. Zombie Fungus From 'The Last of Us': Is It Real?

    Feb 16, 2023 · The fungus from The Last of Us is based on a real fungus that exists in nature today and is called Ophiocordyceps unilateralis, or cordyceps. Cordyceps is often referred to …