Multiple sclerosis is the most common cause of progressive neurologic disability in young adults. There had been no ...

Chimeric antigen receptor (CAR) T cells targeting CD19 have transformed the treatment of B-cell cancers, but many patients do not have long-term remission. We designed an anti-CD19 enhanced ...

Obicetrapib is a highly selective cholesteryl ester transfer protein inhibitor that reduces low-density lipoprotein (LDL) cholesterol levels. The efficacy and safety of obicetrapib have not been ...

The aldosterone synthase inhibitor lorundrostat may be an effective treatment for uncontrolled, treatment-resistant hypertension. New research findings are summarized in a short video.

A total of 181 patients underwent randomization and received at least one dose of efruxifermin or placebo. Of these patients, liver biopsy was performed in 154 patients at 36 weeks and in 134 ...

Shown are the genetic variants identified in EPO, the gene encoding erythropoietin (EPO), in patients with erythrocytosis. The term cDNA denotes complementary DNA, F female, M male, and NA not ...

Mycobacterium tuberculosis continues to cause substantial illness globally. The efficacy of BCG revaccination for the prevention of sustained M. tuberculosis infection is unclear. New research ...

In patients with COPD, eosinophilic inflammation leads to exacerbations, with increased use of health care resources and mortality. New research findings with mepolizumab treatment are summarized ...

Hypoxemia occurs early during an attack and, as indicated by the low carbon dioxide tensions, is not the result of overall underventilation. In that regard asthmatic patients act like the group of ...

Christopher Duggan is the director of the Center for Nutrition at Boston Children’s Hospital, a professor of pediatrics at Harvard Medical School, and a professor in the Departments of Nutrition ...

Arthur Robin Williams is an associate professor of clinical psychiatry at Columbia University and a research scientist at the New York State Psychiatric Institute. Stephen Morrissey, the ...