Different DNA Structures Nucleate the Folding of Proteins to form specific complexes that modulate the readout of ...

A growing body of genetic evidence suggests that Neanderthals and Denisovans carried many of the same regulatory gene networks linked to language and vocal anatomy in modern humans, challenging the ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...

The brain’s ability to do everything from forming memories to coordinating movement relies on its cells producing the right proteins at the right time. But directly measuring this protein production, ...

A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. They have revealed a unique viral mechanism: A molecular ring anchors the viral copying machine ...

The atomic structural analysis also revealed the role of the so-called capping enzyme. It is stably integrated into the complex and ensures that the newly formed viral mRNA is immediately provided ...

A DNA nano-harvester stays on its track inside tumor cells, measuring cancer aggressiveness by detecting a key microRNA ...

New findings from Karolinska Institutet reveal how the gene HNRNPU coordinates several fundamental molecular processes during ...

A DNA-based nanodevice applies controlled force to individual proteins, enabling researchers to observe molecular changes and ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...