Recent research on human evolution suggests that the extinction of our Neanderthal cousins may have been hastened by ...

The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in shaping ...

Cardiovascular disease continues to be the leading cause of death worldwide. But advances in heart-failure therapeutics have ...

A Czech scientist has contributed to understanding the function of the thymus—the training center of the immune system. T ...

This story has been updated. The human immune system is our body’s primary line of defense against harmful microbes, viruses and other invaders—but that defense line can sometimes run amok and attack ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

The team succeeded in turning T cells from mice suffering autoimmune diseases into stable regulatory T cells with a special ...

Sakaguchi's 1995 discovery of regulatory T cells revealed a complex immune tolerance system beyond central tolerance. Brunkow and Ramsdell identified the Foxp3 gene mutation in 2001, linking it to ...

Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi were awarded the 2025 Nobel Prize in Physiology or Medicine on Monday for their collective work in the discovery of specialized immune cells that roam ...