Neurons have a "hibernation mode." Scientists discover how brain cells use RNA tentacles to lock their protein factories together to survive when energy is low.

The mitochondria, perhaps better known as the powerhouse of the cell, is emerging as a possible factor in the pains of aging.

Yeast, worms, and mice remodel their endoplasmic reticulum early in the aging process. The protective shift offers potential targets to extend healthy lifespan.

A buildup of a structural protein called F-actin inside aging brain cells appears to cripple the cellular waste-clearing machinery that keeps neurons healthy, according to a study in Drosophila fruit ...

As humans and other animals grow old, our cells modify their endoplasmic reticulum (ER) – an extensive transport system that plays a critical role in various biochemical processes such as protein ...

Many insects rely on heritable bacterial endosymbionts for essential nutrients that they cannot get through their diet. A new study, published in Nature Communications, indicates that the genomes of ...

When HHMI Investigator Amita Sehgal started studying sleep 25 years ago, the topic elicited a yawn from most biologists. "In ...

From molecular chaperones to mitochondrial failure, discover how heat reshapes the human transcriptome and drives the biological cascade that links rising temperatures to organ injury and public ...

Molecular dynamics simulations yield thermodynamic and time-dependent behavior, elucidating the role of intrinsically ...

Advances in public health and medicine have helped people live longer than ever before. However, those extra years are often affected by poor health ...

Dr. Emanuel is a physician and a professor of medical ethics and health policy at the University of Pennsylvania. I’ve taught the same course to a class of undergraduate, M.B.A., medical and nursing ...