Introduction Evidence of treat-to-target strategies including secukinumab dose escalation in patients with axial spondyloarthritis (axSpA) remains limited. We investigated the effect of a ...

Background Diffuse idiopathic skeletal hyperostosis (DISH) is characterised by ossification of the spine including the anterior longitudinal ligament. While often still considered a pure radiographic ...

Objective To examine associations between participants’ perinatal factors, including harmonised birth weight and length, ...

Objectives To determine the prevalence of depressive and anxiety symptoms among young people 7 years and 9 years after ...

Introduction Antiphospholipid syndrome (APS) is an autoimmune disease characterised by obstetric morbidity and recurrent ...

Objective Although socioeconomic status has been linked to various rheumatoid arthritis (RA)-related outcomes, evidence on ...

Assessing the presence and degree of synovitis is the cornerstone of managing patients with arthritis. Ultrasound has been ...

Objective Postmarketing safety data of avacopan, the first Food and Drug Administration (FDA) approved drug in a decade for antineutrophil cytoplasmic antibody-associated vasculitis (AAV), are ...

Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous autoimmune disease with multifactorial pathogenesis. Although polygenic risk scores (PRSs) have been developed to enable ...

Data sources Medline, Embase, Epistemonikos, PEDro, Cochrane and registries from inception to 8 November 2025. Eligibility criteria Reviews comparing exercise with placebo, no intervention or other ...

Objectives This prespecified interim analysis of the PRO-SPIRIT observational study compares the effectiveness and persistence of ixekizumab (IXE) with other biologic or targeted synthetic ...

Music therapy is recognised as a complementary or alternative therapy for osteoarthritis and fibromyalgia, but playing music can have health repercussions for musicians in the field of rheumatology.