The defense. The Titans lost a trio of safeties to injuries after a couple of series. They also allowed seven straight ...

According to recent reports, free agent right-handed pitcher Michael King has narrowed his search down to three teams, and ...

Two defensive stars were lost for the season. Their QB missed multiple games. Still, here are the 49ers are, a game out of ...

It's clear the 49ers are relying on Pearsall to become Aiyuk's successor in the receiving corps — this season and in the ...

The San Francisco 49ers’ wide receiver problems grew earlier this week when they placed Brandon Aiyuk on the reserve/left squad list.

SANTA CLARA — Christian McCaffrey will continue his two-pronged assault on a 49ers’ playoff berth as well as his quest to ...

The San Francisco 49ers finished their Week 15 contest with a 37-24 win over the Tennessee Titans at Levi's® Stadium.

Jeffery Simmons made a remarkable impact for the Tennessee Titans in their 37-24 loss to San Francisco on Sunday.

The San Francisco 49ers hosted a halftime ceremony this Sunday to celebrate the induction of three-time Super Bowl champion Brent Jones into the Edward J. DeBartolo Sr. San Francisco 49ers Hall of ...

SANTA CLARA, Calif. (AP) — Brock Purdy threw three touchdown passes and the San Francisco 49ers started the stretch run of ...

The Niners officially placed Aiyuk on the NFL’s reserve list on Saturday, with a “left squad” designation. It’s an incredibly ...

Listed as inactive for the 49ers were wide receiver Jordan Watkins, running back Jordan James, linebacker Nick Martin, ...