Naoya Inoue put his undisputed super bantamweight title on the line against Ramon Cardenas at the T-Mobile Arena in Las Vegas May 4. Inoue came into the contest looking to add another knockout to his collection.

Cardenas then flipped the entire fight in the second round. After showing more aggression and forcing Inoue backward early in the round, Cardenas took advantage of Inoue's attempt to return the aggression and landed a left hook counter, dropping Inoue to the canvas in a shocking moment.