Their study shows that the by-product, called Hydrocholesterol 24-OHC or 24-OHC, is responsible for the formation of Lewy ...

Hydrocholesterol 24-OHC associated with dopamine neuron degeneration and Levy body formation Date: February 18, 2025 Source: PLOS Summary: Researchers have discovered a cholesterol metabolite that ...

Studies in mice, led by Zhentao Zhang, MD, PhD, indicated that the metabolite, 24-hydroxycholesterol (24-OHC), promotes the spread of Lewy bodies and the death of dopaminergic neurons in the brain ...

24(S)-hydroxycholesterol (24S-OHC), which is enzymatically produced in the brain, has an important role in maintaining brain cholesterol homeostasis. We have previously reported that 24S-OHC ...

Their study shows that the by-product, called Hydrocholesterol 24-OHC or 24-OHC, is responsible for the formation of Lewy bodies and the death of dopaminergic neurons in the brain - the two major ...

In particular, 25-hydroxycholesterol (25-OHC) has been shown to contribute to arteriosclerosis, cancer development, central nervous system disorders, dysregulated immune responses, and macular ...

Chinese scientists say preventing cholesterol from being converted to 24-OHC might be an effective treatment for Parkinson's disease. Skip to main content. You have permission to edit this ...