The 7β-hydroxycholesterol concentrations were determined at the Karolinska Institute by isotope dilution–mass spectrometry and the use of a deuterated internal standard. 21 In addition, ...

25-hydroxycholesterol (25-HC) plays a role in the regulation of cell survival and immunity. However, the effect of 25-HC on myocardial ischemia/reperfusion (MI/R) injury remains unknown. Our present ...

Increased 25-Hydroxycholesterol as an indicator for patients with vestibular neuritis Provisionally accepted . Xuhua Song Jingwei Liang Congzhe Tian * Affiliated Hospital of Hebei University, Baoding, ...

In a previous work we generated mice with a disruption of 3β-hydroxysteroid-Δ 24-reductase (desmosterol reductase, Dhcr24), as a result of which cholesterol synthesis is blocked because of absence of ...

The test is used to check kidney function. A 24-hour urine collection is done by collecting your urine in a special container over a full 24-hour period. The container must be kept cool until the ...

Tertiary sulfonamides were identified in a HTS as dual liver X receptor (LXR, NR1H2, and NR1H3) ligands, and the binding affinity of the series was increased through iterative analogue synthesis. A ...

It has been demonstrated that extrinsic factors play an essential role in the activation of EMH (Short et al, 2019).Overexpression of Tlx1, a transcription factor expressed in spleen stromal cells, ...