The combination of 20- and 22-hydroxycholesterol (20-OHC and 22-OHC; see Fig. 2) promotes the differentiation of bone and inhibits the differentiation of adipose tissue from mesenchymal stem cells 61.

In a recent clinical study, Leoni et al. 2 showed that concentrations of 24S-hydroxycholesterol, ... This intrabrain metabolism of cholesterol is ensured by cholesterol 24- hydroxylase, ...