Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

New research has identified the pain pathways between the gut and brain Researchers have identified the nerve pathways responsible for pain signals from the bowel to the brain, paving the way for new ...

A single neural thread in the brain may explain why some people who are hurt lash out while others turn the pain inward. A new study published in Science Advances reveals that early-life trauma can ...

So when you touch a hot stove, the nerve endings in your fingers react instantly. But the ouch comes a split-second later, when that information finally reaches your brain. Well, now, scientists have ...

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering. The breakthrough challenges our beliefs about how we process pain and may ...

A variety of pain-relieving drugs are available both over the counter and by prescription. SelectStock/Vetta via Getty Images Without the ability to feel pain, life is more dangerous. To avoid injury, ...

René Descartes gave a colorful description of the mechanism of pain in the 17th Century: "Particles" of fire set in motion a spot on the skin of the foot, and by means of a "delicate thread" they open ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...