According to SportsLine's Inside the Lines team, Indianapolis on Monday night has much more to lose in Week 16 ...

Upsets have some extra juice to them in the final stretch of the season, as they could have a significant impact on the ...

The San Francisco 49ers have a big Week 16 Monday Night Football clash against the Colts, and here are bold predictions.

The Colts desperately need a win in Week 16 against the 49ers. Here are 3 Colts bold predictions before their huge MNF game.

Let’s keep the streak going. We have found some success with our NFC West Bold Predictions, but now the heat is on. The Los ...

NFL Week 16 is here, so let's look at the odds and make some picks and predictions for the coming weekend as the playoffs ...

In a battle for first place in the NFC West and the No. 1 seed, the LA Rams visit the Seattle Seahawks Thursday night.

Welcome back to our NFL Pick'em Pool Picks for Week 16 of the 2025 NFL season. The playoff picture is nearly set in both ...

Rivers' comeback is a feel-good story, but is it good for the Colts? Meanwhile, we like the Seahawks and Bears in tight ...

Nissan Stadium is the location where the Tennessee Titans (2-12) will meet the Kansas City Chiefs (6-8) on Sunday. Kansas ...

ESPN's FPI simulation projects how the 49ers finish the 2025 season, their playoff seed, and how far San Francisco advances.

We make picks for all 16 NFL games with levels of confidence ahead of Week 16. We’re a week away from Christmas and the NFL ...