A research group led by Professor Tomoyuki Furuyashiki and Associate Professor Shiho Kitaoka (Graduate School of Medicine) in collaboration with researcher Yasuhisa Ano of Kirin Holdings have made ...

Researchers have made discoveries regarding the effect of the dipeptide Leucine-Histidine (LH) in suppressing microglial activation and depression-associated emotional disturbances. LH dipeptide is ...

Scientists trying to understand what is toxic about the C9ORF72 hexanucleotide expansion, linked to amyotrophic lateral sclerosis and frontotemporal dementia, have implicated two different RNA repeats ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2–BECN1 interaction.

Lots of evidence suggests dipeptide repeat proteins translated from hexanucleotide repeat expansions in C9ORF72 interfere with transport of proteins in and out of the cell’s nucleus. However, an ...

The GFP family is one of the most important systems used for lighting up biological macromolecules in living environments 5,6. Following the initial structural characterization of the native GFP, many ...

Heme, a major iron source, is transported through the outer membrane of Gram-negative bacteria by specific heme/hemoprotein receptors and through the inner membrane by heme-specific, periplasmic, ...

Carnosine is a dipeptide, derived from beta-alanine and histidine, that is abundantly found in muscle and brain tissues and provides a range of health advantages. In recent years, there has been a ...

University of North Carolina (UNC) researchers Taghreed Al-Turki, PhD, and Jack Griffith, PhD, have made the discovery that the telomeres on the ends of chromosomes contain genetic information that ...

Masao Takagaki, Walda Powell, Anop Sood, Bernard F. Spielvogel, Narayan S. Hosmane, Mitsunori Kirihata, Koji Ono, Shin-Ichiro Masunaga, Yuko Kinashi, Shin-Ichi Miyatake and Nobuo Hashimoto Radiation ...