One of the biggest challenges in cancer treatment is chemoresistance: Tumors that initially respond well to chemotherapy ...

Ribbon structure of the BRCA2 protein. Mutations in the BRCA2 gene are linked to increased risk of breast cancer. New work from UC Davis shows how individual BRCA2 proteins work to repair damaged DNA, ...

Over the the next five years, up to 100,000 people in Ontario will be screened for genetic conditions that increase their ...

Pancreatic cancer incidence is rising among younger adults, particularly those aged 15 to 39, due to lifestyle and genetic factors. Key risk factors include obesity, smoking, alcohol consumption, and ...

One of the biggest challenges in cancer treatment is chemoresistance: tumors that initially respond well to chemotherapy ...

The initials BRCA2 may be best known for a gene associated with many cases of breast cancer, and the protein encoded by the BRCA2 gene is critical to repairing breaks in DNA. The breakdown of this ...

Women with ovarian cancer who have the BRCA2 gene mutation are more likely to survive the malignancy than women with the BRCA1 mutation, or women without either mutation, according to new research.

At this point, you're probably familiar with BRCA1 and BRCA2 mutations, those faulty gene copies that can raise your risk of breast and ovarian cancer. Angelina Jolie, for example, carries a BRCA1 ...

The structural integrity of DNA is continually being challenged due to the presence of physical and chemical carcinogens in our environment. In addition to DNA lesions caused by exogenous agents, DNA ...

new study shows exactly how the gene BRCA2, linked to susceptibility to breast and ovarian cancer, functions to repair damaged DNA. By studying BRCA2 at the level of single molecules, researchers at ...