Please provide your email address to receive an email when new articles are posted on . The findings, presented at ASH Annual Meeting and Exposition, shine a light on underrecognized alterations that ...

Acute myeloid leukemia (AML) starts in the bone marrow, but often quickly moves into the blood, as well. The main treatment for most types of AML is chemotherapy, sometimes along with a targeted ...

Acute myeloid leukemia driven by tandem duplications within the UBTF gene (UBTF-TD AML) is a high-risk pediatric cancer in urgent need of novel therapeutic options. To better understand this disease ...

The mutation is more common than expected and associated with poor outcomes, according to researchers from St. Jude Children’s Research Hospital. In addition, 417 patients from previous studies were ...

Scientists at St. Jude Children’s Research Hospital have found a previously overlooked mutation in a subtype of pediatric leukemia that has implications for identifying high-risk patients. St. Jude ...

Tandem duplication in UBTF is associated with a resistant form of AML. A menin inhibitor induced a short-lived response. Resistance was associated with mutations at the drug-binding site in MEN1, w ...