Every cell in the body has the same DNA, but different cell types—such as muscle or brain cells—use different parts of it.

Michael Buck, PhD, professor of biochemistry in the Jacobs School, recently received NIH funding to explore how molecular readers of DNA access and activate seemingly hidden genes.

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's ...

MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, tiny loops called microcompartments remain (and even strengthen) while ...

Northwestern Medicine scientists have discovered how a specific transcription factor promotes genetic reprogramming and ...

Approach that uses cell’s own strategy of liquid-liquid phase separation protects synthetic modifications from being washed away by the tide of cell growth.

Liver fibrosis is a major health threat, and current therapies remain limited. To advance treatment options, researchers at ...

Could yeast and humans be any more different? Going by looks alone, probably not. But peering into our genomes reveals ...