Recent clinical trials for malignant glioma have drawn attention to the potential therapeutic efficacy of herpes simplex virus-thymidine kinase (HSV-tk) suicide gene therapy. Nevertheless, because of ...
Pro-drug activation gene therapy using Herpes Simplex virus thymidine kinase (HSV-tk) gene transduction in combination with ganciclovir (GCV) is under investigation as a potential cancer therapy.
Aims: Previous studies revealed that drug-loaded poly(ethylene-glycol)-poly(γ-benzyl-L-glutamate) (PEG-PBLG) nanoparticles exhibit favorable pharmacokinetic ...
MolMed S.p.A. has announced that the European Patent Office granted a key patent covering the gene forming the basis of TK, MolMed's investigational cell therapy product currently in Phase III for the ...
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