Despite centuries of study, scientists are still finding new details and even overlooked structures within the human body. As researchers explore anatomical differences between individuals, it’s ...
Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent
The circadian clock regulates cellular and molecular processes in mammals across all tissues including skeletal muscle, one of the largest organs in the human body. Dysregulated circadian rhythms are ...
Full view of how bones and joints form in the first trimester uncovers cells and pathways that could help diagnose and treat skeletal conditions in the future. The first 'blueprint' of human skeletal ...
Vitamin D status modulates mitochondrial oxidative capacities in skeletal muscle: role in sarcopenia
Skeletal muscle mitochondrial function is the biggest component of whole-body energy output. Mitochondrial energy production during exercise is impaired in vitamin D-deficient subjects. In cultured ...
The human body is often described as a marvel of “perfect design”: elegant, efficient and finely tuned for its purpose. Yet, when we look closer, a rather different picture emerges. Far from being a ...
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