Coordination of microtubules and the actin cytoskeleton is important in several types of cell movement. mDia1 is a member of the formin-homology family of proteins and an effector of the small GTPase ...

Plant growth and development are a genetically predetermined series of events but can change dramatically in response to environmental stimuli, involving perpetual pattern formation and reprogramming ...

A KAIST research team has discovered that the Huntington protein originally plays a critical role in forming the neuronal cytoskeleton under normal conditions. The findings were published in the ...

Actin filaments (F-actin) are key components of sarcomeres, the basic contractile units of skeletal muscle myofibrils. A crucial step during myofibril differentiation is the sequential exchange of ...

Huntington's disease is a rare genetic disorder and a representative neurodegenerative disease, characterized by loss of ...

Like poles support a tent, microtubules—hollow cylindrical structures made of tubulin protein—support eukaryotic cells. But microtubules provide more than just mechanical strength; they help prepare ...

Researchers have developed photoresponsive derivatives of the anticancer drug Taxol®, which allow light-based control of cytoskeleton dynamics in neurons. The agents can optically pattern cell ...

Proteins containing disordered domains perform many important cellular functions. My lab currently has two main projects, one to dissect the role of tubulin's C-terminal tail in microtubule structure ...