The Israeli study examined tumor samples and nearby lymph nodes from 11 patients with high-grade serous ovarian cancer.

Emerging evidence indicates that memory B cells are dysfunctional in systemic lupus erythematosus (SLE). They are hyporesponsive to signalling through the B cell receptor (BCR) but retain ...

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

B cell depletion with rituximab, a chimeric monoclonal antibody that selectively targets B cells by binding CD20, has been used off label in severe and resistant systemic lupus erythematosus (SLE) for ...

T-bet expression is required for persistence of memory B cells that have rapid differentiation potential to become antibody-producing plasma cells in response to a second infection BIRMINGHAM, Ala. – ...