A third heart sound, or S3, is a low-frequency, extra heart sound that may be heard with a stethoscope right after the normal S1 and S2 heart sounds. S1 and S2 are the "lub-dub" sounds of a heartbeat ...

An S4 heart sound cannot be present during atrial fibrillation (atrial kick is required). An S3 heart sound cannot be present in the setting of severe mitral stenosis. An S3 heart sound can be present ...