Proper expression of proteins in eukaryotic cells requires precise stitching of protein-coding fragments, or exons, from precursor mRNAs that also contain non-coding introns. This process, known as ...
Combinatorially, intron excision within a given nascent transcript could proceed down any of thousands of paths, each of which would expose different dynamic landscapes of cis-elements and contribute ...
Platelets are anucleate cytoplasmic fragments, deriving from precursor megakaryocytes, which play key roles in processes such as thrombosis, hemostasis, inflammation, wound healing and angiogenesis.