Chronic Intestinal Pseudo-Obstruction (CIPO) and related gastrointestinal motility disorders constitute a group of rare but debilitating conditions that mimic mechanical obstruction despite the ...

Maternal health and other events occurring during pregnancy determine the health outcomes in offspring. Pre-natal infections are a major risk factor contributing to compromised intestinal barrier ...

Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal motility ...

A multi-institutional group of researchers led by the Hubrecht Institute and Roche's Institute of Human Biology has developed strategies to identify regulators of intestinal hormone secretion. In ...

Scientists show that the receptor PIEZO2 in sensory neurons controls gut motility and transit time, which are important for digestion and nutrient absorption. Gastrointestinal and digestive issues ...

Anxiety affects gut motility, causing diarrhea or constipation, and can exacerbate conditions like IBS by altering intestinal contractions. Stress increases intestinal inflammation by weakening the ...

As GLP-1 use rise, constipation remains a leading cause of discontinuation. Experts offer practical strategies for prevention and management.

Gastroparesis is a chronic gastrointestinal (GI) condition affecting the nerves and muscles that help your stomach empty itself. When the stomach can’t move well, food sits inside, resulting in ...