Their study highlights the role of support cells known as astrocytes in generating excessive mitochondrial reactive oxygen species at a specific site — mitochondrial Complex III — and suggests that ...

There are numerous different scenarios in which microorganisms are exposed to highly reactive molecules known as free radicals. These molecules are capable of damaging important cell components and ...

A study by University of Manchester scientists has revealed some of the mechanisms which may explain why older mice are more ...

Researchers have discovered that free radicals generated at a specific site in non-neuronal brain cells called astrocytes, ...

Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that ...

Tests on mice with dementia showed S3QELs reduced brain inflammation, even in late treatments - Anadolu Ajansı ...

Free radical chemistry centres on the study of species that possess one or more unpaired electrons – a feature that confers unique reactivity and diverse roles across chemical and biological systems.

Sigma-1 receptors (Sig-1Rs) are endoplasmic reticulum (ER)-resident proteins known to be involved in learning and memory. Dendritic spines in hippocampal neurons play important roles in ...

Many different mechanisms have been suggested for the oxidative lipid fragmentations that produce biologically active aldehydes such as 4-hydroxynon-2-enal (HNE), oxononanoyl phosphatidylcholine ...