Medscape

Oxidative Injury and Apoptosis of Dorsal Root Ganglion Neurons in Chronic Experimental Diabetic Neuropathy

We evaluated the effects of chronic hyperglycemia on L5 dorsal root ganglion (DRG) neurons using immunohistochemical and electrophysiologic techniques for evidence of oxidative injury. Experimental ...
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Toxicity of dorsal root ganglia is widely associated with CNS AAV gene therapy

New Rochelle, NY, September 2, 2020—A meta-analysis of non-human primate (NHP) studies showed that adeno-associated virus (AAV) gene therapy often caused dorsal root ganglion (DRG) pathology. There ...
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Nageotte nodules in human dorsal root ganglia in a case of diabetic peripheral neuropathy (IMAGE)

Human dorsal root ganglia in a case of diabetic peripheral neuropathy show formation of Nageotte nodules (circled in pink), which appear to be a strong indicator of nerve cell death. Disclaimer: AAAS ...
Medscape

Oxidative Injury and Apoptosis of Dorsal Root Ganglion Neurons in Chronic Experimental Diabetic Neuropathy

There are several findings of this study. First, there is early development of neuropathy electrophysiologically, with more pronounced involvement of sensory fibers followed by a combined sensorimotor ...