Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control when and how genes are switched on.

The laws of inheritance are quite unknown,” Charles Darwin acknowledged in 1859. The discovery of DNA’s shape altered how we conceived of life itself.

MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, tiny loops called microcompartments remain (and even strengthen) while chromosomes condense.

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated—able to read not only the code itself,

Sections of DNA once dismissed as dormant and useless could in fact be recruited to fight certain types of drug-resistant blood cancers, new research has revealed. Known as 'junk' DNA, these bits of DNA don't encode proteins,

King’s College London researchers discovered that parts of our DNA once thought to be “junk” can actually help destroy cancer cells. In some blood cancers, damaged genes trigger chaos in these DNA segments,

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that provides vital chemical units for the synthesis of DNA,

A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including that seen in motor neuron, Alzheimer’s and Parkinson’s diseases. Macquarie ...