In yeast, the CDK and cyclin proteins that drive cell division activate first in the nucleus — a different location in the cell from where was previously thought. James E. Ferrell Jr is in the ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell’s nucleus. The ...

An international team of scientists has unveiled the most comprehensive model yet that explains how cells control the flow of materials in and out of their nuclei—solving one of biology's oldest ...

The cytoskeleton gives cells their shape and helps them move. Researchers at Helmholtz Munich and the Ludwig Maximilian University now show that, in neural stem cells, proteins of the cytoskeleton are ...

Back 2.8 billion years ago, while Earth shifted its plates to make new continents and violent volcanoes produced new crust, life crafted a novel invention of its own. 1,2 At first, the nucleus was ...

An international team of researchers has created the most detailed model yet of how cells regulate traffic through the nuclear pore complex—the gateway between a cell’s nucleus and its cytoplasm. The ...