Scientists have been unable to determine the structure of a biologically important so-called GAG proteoglycan -- or even to agree whether these remarkably complex molecules have well-defined ...

Carbohydrates are ubiquitous. They densely carpet cell surfaces. They are the main component of the extracellular matrix that surrounds cells. They are involved in many aspects of cell-cell ...

Despite mass spectrometry's success in the identification and characterization of small molecules (Milestone 7), its application to carbohydrates was initially stymied. This was due to their low vapor ...

Carbohydrates, as the name suggests, refers to the hydrates of carbon comprising carbon, hydrogen and oxygen. The hydrogen and oxygen present in carbohydrates is in the ratio of 2:1. Carbohydrates are ...

Recent advances in both molecular dynamics (MD) simulations and nuclear magnetic resonance (NMR) spectroscopy have significantly enhanced our understanding of carbohydrate structure and dynamics.

Researchers have identified a specific carbohydrate structure that confers anti-inflammatory activity to a glycoprotein antibody that could lead to improved treatment of autoimmune diseases like lupus ...

Characterization of the carbohydrate portion of glycoproteins in a high-throughput, cost-efficient manner presents myriad technological challenges. Unlike the linear peptide components of these ...

Nobody would argue with the statement that proteins are a challenge for computer modelers. Descriptions of their swirls of helices and ribbons, to say nothing of their further folding, can tax even ...

The Max Planck Institute of Colloids and Interfaces (MPICI) has created a carbohydrate sequence that can fold into a stable secondary structure. To date, self-folding biopolymers had only been ...

DURHAM, N.H. – Researchers at the University of New Hampshire Glycomics Center have helped identify a specific carbohydrate structure that confers anti-inflammatory activity to a glycoprotein antibody ...