Claiborne arrived in Natchez only a few months before a smallpox epidemic hit the Mississippi ... By the 1700s, the British ...

This account of the recent epidemic of smallpox in Boston forms part of a report upon smallpox and vaccination prepared, at the request of the Sanitary Association, by Dr. J. C. White and myself.

By the time sailing ship Capt. Robert Gray named and claimed the Columbia River for the United States in 1792, European diseases already had decimated the Pacific Northwest Native American population.