Explore the concept of heterozygote advantage and its role in balancing selection affecting allele frequencies. The critical point I want to make is that while positive selection will usually tend to ...

Instances in which natural selection maintains genetic variation in a population over millions of years are thought to be extremely rare. We conducted a genome-wide scan for long-lived balancing ...

A new study explores 'balancing selection' by analyzing thousands of modern human genomes alongside ancient hominin groups, such as Neanderthal and Denisovan genomes. The research has 'implications ...

In humans, the pervasiveness of hard sweeps (that is, for strong selection to drive the rapid fixation of new mutations in particular populations) has been strongly argued against. As an alternative, ...

The importance of interspecific introgression as a source of adaptive variation is increasingly recognized. Theory predicts that beneficial genetic variants cross species boundaries easily even when ...