DraftKings has them at -750 and FanDuel has them at -590. The implied odds on that are 88% and 85% respectively. NFL.com has a playoff projection system that gives them an 86% chance of making it, while ESPN FPI has them at 90%. Lastly, FTN, the home of DVOA, has them at 86% and the Athletic has matched that in their projections as well.

The San Francisco 49ers beat the Arizona Cardinals on Sunday at State Farm Stadium. How did it affect their standing heading into Week 12?

San Francisco 49ers QB Brock Purdy and his favorite target George Kittle have benefitted from their connection in more ways than one over the years

Jason Pinnock was benched after Week 5, but he has played 80 snaps in the 49ers' dime look since then. However, he has not been good in that role. Pinnock allowed five catches, including a touchdown, in his expanded role against the Arizona Cardinals. That should signal a time to switch things up, as he was one of the few issues in that game.

The Arizona Cardinals dropped to 3-7 with their 41-22 loss to the San Francisco 49ers, but quarterback Jacoby Brissett was able to make NFL history in the process.

Albert Breer and Kyle Brandt argue that San Francisco 49ers coach Kyle Shanahan deserves consideration for the 2025 NFL Coach of the Year award.

The San Francisco 49ers made a small tweak to their practice squad ahead of the start of their Week 12 practices.

CBS Sports draft analyst Mike Renner has released his fourth 2026 NFL mock draft, projecting that the San Francisco 49ers will address one of their most pressing needs.